Vogel Test

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Vogel Test

Vogel Test Apparatus or Vogel Test Anxiometer is used for screening of anxiolytic effects of drugs on small laboratory animals like mice and rat.

The Vogel test is a conflict test has become a standard for fast screening the potential anxiolytic properties of drugs. In this procedure, the drinking behaviour is punished by mild electrical shocks leading to a significant reduction of water consumption in deprived animals. Drinking responses are then re-established by drugs with anxiolytic properties.

Vogel test consists of a standard home cage for mice as well as rat associated with a grid floor. An electronic unit associated with a special nipple ensures the detection and counting of the licks reflecting the animal drinking behaviour.

Orchid’s Vogel Test Apparatus is designed to induce anxiety within a subject and monitor the degree of drug effect by the administration of a mild shock after 20 licks on a sipper tube. The shock is delivered through the sipper tube and is maintained for a selectable duration of 0.25 to 2.0 seconds. The intensity of shock is user adjustable. With the onset of the initial shock, Anxiometer begins a three minute testing session during which the total number of licks and shocks (administered with every 20th lick) is recorded on front panel counters. The performance of anti-anxiety drugs can be measured by comparing the drinking behaviour of punished drugged rats to the behaviour of punished non-drugged rats.

Features

  • Specially designed water bottle making lick count & shock delivery only on water contact and not on sipper tube contact
  • Software for data collection and data can be converted to excel or Pdf
  • Provision to add experiment name and comment facility in software report
  • Parameters calculated: Number of licks and Number of shocks
  • Adjustable parameters: Shock Duration: 0.25s to 2s , Shock Intensity: 100µA to 2.9mA, Number of licks for giving shock: 1-99, Duration of test period: 1-99 min

System Specification & Models

Cage Provided
ModelVTA 01
Mice cagePolycarbonate cage of size 29x22x14 cm with S.S. top grill and floor supplied with 125ml water bottle
Rat CagePolycarbonate cage of size 43x29x20cm with S.S. top grill and floor supplied with 250ml water bottle

Order Information

ModelCertificationsPower requirements Accessories
VTA- 01CE Compliant220/230V AC 50Hz
110/110V AC 50-60Hz*
Mice cage- Polycarbonate mice cage of size 29x22x14cm, with 150ml water bottle, top and floor S.S. 304 Grill,

Rat cage- Polycarbonate rat cage of size 43x29x20cm, with 250ml water bottle, top and floor S.S. 304 Grill,

CD for software,

RS232 Cable,

RS232 to USB converter

*Needs to be specified in order information

 

Note: Orchid’s continuing product development makes specifications subject to change without prior notification.

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